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España , Betacoronavirus , Pandemias , Obtención de Tejidos y Órganos , Trasplante de Órganos , Donantes de SangreRESUMEN
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Asunto(s)
Humanos , Crioglobulinemia , Hepatitis C , Trastornos LinfoproliferativosRESUMEN
The simultaneous occurrence of two different histologic types of lymphoma in one location ("composite" lymphoma) or in different anatomical locations ("discordant" lymphoma) is uncommon, particularly the association of Hodgkin's disease (HD) and non-Hodgkin's disease (NHD). Therefore, both conditions have long been considered well differentiated entities, and its association qualified as a chance event. Two cases of "discordant" lymphoma are reported. In both cases the histologic type was HD with mixed cellularity, associated with immunoblastic B lymphoma in case 1 and CLL-B in case 2. Some recent series seem to indicate that this phenomenon occurs more commonly than what could be reasonably attributed to chance alone, suggesting the analysis of cases associating HD and NHD with CLL-B a possible clonal relationship between these conditions. The Reed-Sternberg cell might thus originate from an altered B-lymphocyte.
Asunto(s)
Enfermedad de Hodgkin/patología , Leucemia Linfocítica Crónica de Células B/patología , Linfoma no Hodgkin/patología , Neoplasias Primarias Múltiples/patología , Anciano , Terapia Combinada , Resultado Fatal , Femenino , Enfermedad de Hodgkin/terapia , Humanos , Leucemia Linfocítica Crónica de Células B/terapia , Linfoma no Hodgkin/terapia , Neoplasias Primarias Múltiples/terapia , Recurrencia , Terminología como AsuntoRESUMEN
The clinical histories and thorax X-rays of 91 patients aged between 15 and 25 years who were admitted at the Hospital Royo Villanova, Zaragoza from 1983 to 1987 because of active pulmonary tuberculosis, were reviewed in order to study the radiological presentation of pulmonary tuberculosis in young patients and examine if there were any differences with other age groups. We highlight from the results: 1) The male/female ratio was 1.5/1.2) There were no differences in the radiological presentation between this group and older subjects, 3) The radiological localization of the lesions was the classical one, 4) The mean clinical evolution time before diagnosis was made, was of three months, 5) A longer evolution time was related to a greater lesion extension. We highlight that a prompt X-ray contributes to the early diagnosis of pulmonary tuberculosis in young patients avoiding delays in diagnosis and treatment.
